高知大学 農林海洋科学部 大学院 総合人間自然科学研究科農学専攻

教員情報(研究者情報)

氏名

わかまつ たいすけ

若松 泰介
自己紹介
生年 1981 地域連携情報
学系 総合科学系 高知大学研究者総覧
部門 生命環境医学部門
職名 講師
Tel 088-864-5191
Fax 088-864-5191
e-mail
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学位 理学博士(大阪大学)
専門分野 生化学、蛋白質科学
研究課題 新規有用蛋白質の探索、機能解析・構造解析、そして応用
(1)ポリ-γ-グルタミン酸代謝関連酵素群の立体構造解析
(2)深海底堆積物中で生育する微生物が有する新規有用蛋白質の探索
卒論テーマとして
与えられる課題
新規有用蛋白質の探索、機能解析・構造解析、そして応用
(1)ポリ-γ-グルタミン酸代謝関連酵素群の立体構造解析
(2)発酵食品及び発酵用微生物の生化学的解明とその応用 
共同研究
できる課題
新規有用蛋白質の探索、機能解析・構造解析、そして応用
講演や相談
できる課題
新規有用蛋白質の探索、機能解析・構造解析、そして応用
主な業績や
研究著書

[原著論文] 
1.Yuta Mutaguchi, Taketo Ohmori, Taisuke Wakamatsu, Katsumi Doi, and Toshihisa Ohshima. (2013) Novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species: Identification, purification and characterization. J. Bacteriol. 195, 5207–5215. 2. Yuri Uemura, Noriko Nakagawa, Taisuke Wakamatsu, Kwang Kim, Gaetano T Montelione, John F Hunt, Seiki Kuramitsu, and Ryoji Masui. (2013) Crystal structure of the ligand-binding form of nanoRNase from Bacteroides fragilis, a member of the DHH/DHHA1 phosphoesterase family of proteins. FEBS Lett. 587, 2669–2674. 3. Taisuke Wakamatsu, Chisato Higashi, Taketo Ohmori, Katsumi Doi, and Toshihisa Ohshima. (2012) Biochemical characterization of two glutamate dehydrogenases with different cofactor specificities from hyperthermophilic archaeon Pyrobaculum calidifontis. Extremophiles 17, 379–389. 4. Ying Zhao, Taisuke Wakamatsu, Katsumi Doi, Haruhiko Sakuraba, and Toshihisa Ohshima. (2012) A psychrophilic leucine dehyadrogenase from Sporosarcina psychrophila: purification, characterization, gene sequencing and crystal structure analysis. J. Mol. Catal. B Enzym. 83, 65–72. 5. Shuhei Nakane*, Taisuke Wakamatsu*, Ryoji Masui, Seiki Kuramitsu, and Kenji Fukui. (2011) (*These authors contributed equally to this work.) In vivo, in vitro, and X-ray crystallographic analyses suggest the involvement of an uncharacterized triose-phosphate isomerase (TIM) barrel protein in protection against oxidative stress. J. Biol. Chem. 286, 41636–41646. 6. Kenji Fukui, Taisuke Wakamatsu, Yoshihiro Agari, Ryoji Masui, and Seiki Kuramitsu. (2011) Inactivation of the DNA repair gene mutS, mutL, or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes. PLoS ONE 6, e19053. 7. Taisuke Wakamatsu, Kwang Kim, Yuri Uemura, Noriko Nakagawa, Seiki Kuramitsu, 8. Taisuke Wakamatsu, Yoshiaki Kitamura, Yutaro Kotera, Noriko Nakagawa, Seiki Kuramitsu, and Ryoji Masui. (2010) Structure of RecJ exonuclease defines its specificity for single-stranded DNA. J. Biol. Chem. 285, 9762–9769. 9. Fumiaki Tomoike, Taisuke Wakamatsu, Noriko Nakagawa, Seiki Kuramitsu, and Ryoji Masui. (2009) Crystal structure of Thermus thermophilus HB8 TTHA1606, a conserved hypothetical protein that may be a DNA-binding protein. PROTEINS: Structure, Function, and Bioinformatics 76, 244–248. 10. Naoyuki Kondo, Takashi Nishikubo, Taisuke Wakamatsu, Hirohito Ishikawa, Seiki Kuramitsu, and Ryoji Masui. (2008) Insights into different dependence of dNTP triphosphohydrolase on metal ion species from intracellular ion concentrations in Thermus thermophilus. Extremophiles 12, 217–223. 11. Taisuke Wakamatsu, Noriko Nakagawa, Seiki Kuramitsu, and Ryoji Masui. (2008) Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8. J. Bacteriol. 190, 1108–1117. 12. Yoshihiro Agari, Shinya Sato, Taisuke Wakamatsu, Yoshitaka Bessho, Akio Ebihara, Shigeyuki Yokoyama, Seiki Kuramitsu, and Akeo Shinkai. (2007) X-ray crystal structure of a hypothetical Sua5 protein from Sulfolobus tokodaii strain 7. PROTEINS: Structure, Function, and Bioinformatics 70, 1108–1111. 13. Seiko Yoshikawa, Ryoichi Arai, Yukiko Kinoshita, Tomomi Uchikubo-Kamo, Taisuke Wakamatsu, Ryogo Akasaka, Ryoji Masui, Takaho Terada, Seiki Kuramitsu, Mikako Shirouzu, and Shigeyuki Yokoyama (2007) Structure of archaeal glyoxylate reductase from Pyrococcus horikoshii OT3 complexed with nicotinamide adenine dinucleotide phosphate. Acta Crystallogr. Sect. D Biol. Crystallogr. 63, 357–365.

研究機器等  
特記事項  
キーワード 蛋白質、酵素