高知大学医学部病理学講座
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高知大学医学部
医学科病理学講座

高知県南国市岡豊町小蓮
基礎・臨床研究棟3F西
Tel: 088-880-2330
Fax: 088-880-2332
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高知大学

研究業績

2018年
Taniuchi K, Furihata M, Naganuma S,  Saibara T.
WAVE2 is associated with poor prognosis in pancreatic cancers and promotes cell motility and invasiveness via binding to ACTN4.
 Cancer Med. 2018 Nov;7(11):5733-5751.

Taniuchi K, 
Furihata M, Naganuma S,  Saibara T.
ARHGEF4 predicts poor prognosis and promotes cell invasion by influencing ERK1/2 and GSK-3α/β signaling in pancreatic cancer.  Int J Oncol. 2018 Nov;53(5):2224-2240.

Kikuchi H, Higuchi T, Hashida Y, Taniguchi A, Kamioka M, Taguchi T, Yokoyama A, Murakami I, Fujieda M, Daibata M.
Generation and characteristics of a novel "double-hit" high grade B-cell lymphoma cell line DH-My6 with MYC/IGH and BCL6/IGH gene arrangements and potential molecular targeted therapies.  Oncotarget. 2018 Sep 11;9(71):33482-33499.

Murakami I, Wada N, Nakashima J, Iguchi M, Toi M, Hashida Y, Higuchi T, Daibata M, Matsushita M, Iwasaki T, Kuwamoto S, Horie Y, Nagata K, Hayashi K, Oka T, Yoshino T, Imamura T, Morimoto A, Imashuku S, Gogusev J, Jaubert F.
Merkel cell polyomavirus and Langerhans cell neoplasm.  Cell Commun Signal. 2018 Aug 22;16(1):49.


Kurabayashi A
, Tanaka C, Matsumoto W, Naganuma S, Furihata M, Inoue K, Kakinuma Y.
Murine remote preconditioning increases glucose uptake and suppresses gluconeogenesis in hepatocytes via a brain-liver neurocircuit, leading to counteracting glucose intolerance.  Diabetes Res Clin Pract. 139:288-299.

Taniuchi K, Furihata M, Naganuma S, Dabanaka K, Hanazaki K, Saibara T.  
 BCL7B, a predictor of poor prognosis of pancreatic cancers, promotes cell motility and invasion by influencing CREB signaling.  Am J Cancer Res. 8(3):387-404.


Maeda H, Okamoto K, Oba K, Shiga M, Fujieda Y, Namikawa T, Hiroi M, Murakami I, Hanazaki K, Kobayashi M.
Lymph node retrieval after dissolution of surrounding adipose tissue for pathological examination of colorectal cancer
Oncol Lett. 2018 Feb;15(2):2495-2500.

Toi M, Hayashi Y, Murakami I.
Hepatic stellate cells derived from the nestin-positive cells in septum transversum during rat liver development.  Med Mol Morphol. 2018 Jan 29.

2017年

Tamura K, Furihata M, Satake H, Hashida H, Kawada C, Osakabe H, Fukuhara H, Kumagai N, Iiyama T, Shuin T, Inoue K.
SHISA2 enhances the aggressive phenotype in prostate cancer through the regulation of WNT5A expression.  Oncol Lett. 2017 Dec;14(6):6650-6658.


Machihara K, Tanaka H, Hayashi Y, Murakami I, Namba T.
Questiomycin A stimulates sorafenib-induced cell death via suppression of glucose-regulated protein 78.  Biochem Biophys Res Commun. 2017 Oct 7;492(1):33-40.

Mohri T, Nagata K, Kuwamoto S, Matsushita M, Sugihara H, Kato M, Horie Y, Murakami I, Hayashi K.

Aberrant expression of AID and AID activators of NF-κB and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers. 
Oncol Lett. 2017 Jun;13(6):4133-4140.


Takei Y, Ueshima C, Kataoka TR, Hirata M, Sugimoto A, Rokutan-Kurata M, Moriyoshi K, Ono K, Murakami I, Iwamoto S, Haga H.

Killer cell immunoglobulin-like receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis
Oncotarget. 2017 Jun 6;8(23):36964-36972.

Nagata K, Kumata K, Nakayama Y, Satoh Y, Sugihara H, Hara S, Matsushita M, Kuwamoto S, Kato M, Murakami I, Hayashi K.

Epstein-Barr Virus Lytic Reactivation Activates B Cells Polyclonally and Induces Activation-Induced Cytidine Deaminase Expression: A Mechanism Underlying Autoimmunity and Its Contribution to Graves' Disease
Viral Immunol. 2017 Apr;30(3):240-249.

Okada T, Kurabayashi A, Akimitsu N, Furihata M
.

Expression of Cadherin-17 Promotes
Metastasis in a Highly Bone Marrow Metastatic Murine Breast Cancer Model
Biomed Res Int. 2017;2017:8494286. doi: 10.1155/2017/8494286. Epub 2017 Jan 19.

2016

Tanouchi A, Taniuchi K, Furihata M, Naganuma S, Dabanaka K, Kimura M, Watanabe R, Kohsaki T, Shimizu T, Saito M, Hanazaki K, Saibara T.
CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells.
 J Exp Clin Cancer Res. 2016 Dec 5;35(1):190.

Taniuchi K, Furihata M, Naganuma S, Dabanaka K, Hanazaki K, Saibara T.
Podocalyxin-like protein, linked to poor prognosis of pancreatic cancers, promotes cell invasion by binding to gelsolin.  Cancer Sci. 2016 Oct;107(10):1430-1442.

Tsuboi M, Taniuchi K, Furihata M, Naganuma S, Kimura M, Watanabe R, Shimizu T, Saito M, Dabanaka K, Hanazaki K, Saibara T.
Vav3 is linked to poor prognosis of pancreatic cancers and promotes the motility and invasiveness of pancreatic cancer cells Pancreatology. 2016 Sep-Oct;16(5):905-16.

Kumata K, Nagata K, Matsushita M, Kuwamoto S, Kato M, Murakami I, Fukata S, Hayashi K.
Thyrotropin Receptor Antibody (TRAb)-IgM Levels Are Markedly Higher Than TRAb-IgG Levels in Graves' Disease Patients and Controls, and TRAb-IgM Production Is Related to Epstein-Barr Virus Reactivation.  Viral Immunol. 2016 Oct;29(8):459-463

Hashida Y, Nakajima K, Nakajima H, Shiga T, Tanaka M, Murakami M, Matsuzaki S, Naganuma S, Kuroda N, Seki Y, Katano H, Sano S, Daibata M.
High load of Merkel cell polyomavirus DNA detected in the normal skin of Japanese patients with Merkel cell carcinomaJ Clin Virol. 2016 Sep;82:101-107.

Kuroda N, Yorita K, Naroda T, Hayashi Y, Murakami I
.
Renal oncocytoma, small cell variant, with pseudorosettes, showing cyclin D1 expression and tubulovesicular cristae of mitochondria Pathol Int. 2016 Jul;66(7):409-10.

2015年

Kurabayashi A
, Inoue K, Fukuhara H, Karashima T, Fukata S, Kawada C, Shuin T, Furihata M
.
Combination with third-generation bisphosphonate (YM529) and interferon-alpha can inhibit the progression of established bone renal cell carcinoma.  Cancer Sci. 106(8):1092-1099

Wei S, Fukuhara H, Kawada C, Kurabayashi A, Furihata M, Ogura S, Inoue K, Shuin T.
Silencing of ATPase Inhibitory Factor 1 Inhibits Cell Growth via Cell Cycle Arrest in Bladder Cancer.   Pathobiology. 2015;82(5):224-32.

Fukuhara H, Inoue K, Kurabayashi A, Furihata M, Shuin T.
Performance of 5-aminolevulinic-acid-based photodynamic diagnosis for radical prostatectomy.  BMC Urol. 2015 Aug 1;15:78.

Ohtsuki Y, Fujita J, Yoshinouchi T, Enzan H, Iguchi M, Lee GH, Furihata M.
Early Stages of Hyaline Membrane Formation Detected in Alveolar Mouths in Diffuse Alveolar-Damage-Associated Diseases: A Detailed Immunohistochemical Study.  Int J Surg Pathol. 2015 Oct;23(7):524-30.

Ohtsuki Y, Mori K, Ohnishi H, Enzan H, Iguchi M, Lee GH, Furihata M.
Investigation of aluminum and iron deposition on metaplastic bones in three patients with diffuse pulmonary ossification Med Mol Morphol. 2015 Dec;48(4):235-8.

Memtily N, Okada T, Ebihara T, Sato M, Kurabayashi A, Furihata M, Suga M, Nishiyama H, Mio K, Sato C.
Observation of tissues in open aqueous solution by atmospheric scanning electron microscopy: applicability to intraoperative cancer diagnosis.  Int J Oncol. 2015 May;46(5):1872-82.

2014年

Wei S, Fukuhara H, Chen G, Kawada C, Kurabayashi A, Furihata M, Inoue K, Shuin T.
 Terrestrosin D, a Steroidal Saponin from Tribulus terrestris L., Inhibits Growth and Angiogenesis of Human Prostate Cancer in vitro and in vivo. Pathobiology.  81(3):123- 132

Taniuchi K, Furihata M, Iwasaki S, Tanaka K, Shimizu T, Saito M, Saibara T.
 RUVBL1 directly binds actin filaments and induces formation of cell protrusions to promote pancreatic cancer cell invasion. Int J Oncol. 44(6):1945-1954

Kakinuma Y, Noguchi T, Okazaki K, Oikawa S, Iketani M, Kurabayashi M, Furihata M, Sato T. 
 Antimuscle atrophy effect of nicotine targets muscle satellite cells partly through an α7 nicotinic receptor in a murine hindlimb ischemia model. Transl Res. 164(1):32-45

Taniuchi K, Furihata M, Hanazaki K, Saito M, Saibara T. 
 IGF2BP3-mediated translation in cell protrusions promotes cell invasiveness and metastasis of pancreatic cancer. Oncotarget. 5(16):6832-6845

Taniuchi K, Furihata M, Saibara T.
 KIF20A-mediated RNA granule transport system promotes the invasiveness of pancreatic cancer cells. Neoplasia. 16(12):1082-93

2013年
Nishioka C, Ikezoe T, Furihata M, Yang J, Serada S, Naka T, Nobumoto A, Kataoka S, Tsuda M, Udaka K, Yokoyama A.
 CD34(+) /CD38(-) acute myelogenous leukemia cells aberrantly express CD82 which regulates adhesion and survival of leukemia stem cells. Int J Cancer. 132(9):2006- 2019

Inoue K, Fukuhara H, Kurabayashi A, Furihata M, Tsuda M, Nagakawa K, Fujita H, Utsumi K, Shuin T. 
 Photodynamic therapy involves an antiangiogenic mechanism and is enhanced by ferrochelatase inhibitor in urothelial carcinoma.Cancer Sci. 104(6):765-772

Ueda K, Tatsuguchi A, Saichi N, Toyama A, Tamura K, Furihata M, Takata R, Akamatsu S, Igarashi M, Nakayama M, Sato TA, Ogawa O, Fujioka T, Shuin T, Nakamura Y, Nakagawa H.
Plasma low-molecular-weight proteome profiling identified neuropeptide-y as a prostate cancer biomarker polypeptide. J Proteome Res. 12(10):4497-4506

Inoue K, Ashida S, Fukuhara H, Iiyama T, Miyamura M, Kurabayashi M, Furihata M,
 Application of 5-aminolevulinic acid-mediated photodynamic diagnosis to robot-assisted laparoscopic radical prostatectomy. Urology. 82(5):1175-1178

Fukuhara H, Inoue K, Kurabayashi M, Furihata M, Fujita H, Utsumi K, Sasaki J, Shuin T.
 The inhibition of ferrochelatase enhances 5-aminolevulinic acid-based photodynamic action for prostate cancer. Photodiagnosis Photodyn Ther. 10(4):399-409

Kurabayashi A, Kakinuma Y, Morita T, Inoue K, Sato T, Furihata M.

Conditional VHL gene deletion causes hypoglycemic death associated with disproportionately increased glucose uptake by hepatocytes through an
 upregulated IGF-I receptor.  PLoS One. (2013)


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