Research by Professor Eiki Sano and colleagues from the Department of Dermatology at the School of Medicine has been published in the *British Journal of Dermatology*.
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Research findings by Professor Eiki Sano and colleagues from the Department of Dermatology at our university’s School of Medicine have been published in the British Journal of Dermatology.
Title: Myosin heavy chain, a novel allergen for fish allergy in patients with atopic dermatitis
Identification of a novel allergen associated with fish allergy in patients with atopic dermatitis
(Could touching raw fish with bare hands be the cause!?)
Among food allergies, fish allergies are particularly common and are often difficult to treat or prevent. "Fish parvalbumin" is known to be a major allergen.In this study, Professor Sano and colleagues discovered that myosin heavy chain (MYHC), a large-molecular-weight protein, is a novel allergen associated with fish allergy in atopic dermatitis, and reported their findings in the British Journal of Dermatology. The fact that such large molecules, which do not pass through normal skin, can act as allergens in patients with atopic dermatitis—where the skin barrier is compromised—not only demonstrates the potential for such molecules to trigger allergic reactions but also serves as a warning regarding the risk of developing fish allergies through direct contact with raw fish, such as sushi.